Full length vascular cell adhesion molecule 1 (VCAM-1)
نویسندگان
چکیده
منابع مشابه
Full length vascular cell adhesion molecule 1 (VCAM-1).
We have developed several monoclonal antibodies that bind specifically to IL-1 activated but not to quiescent human unbilical vein endothelial cells (HUVEC). Two antibodies, 1E7 and 2G7, were shown to react at distinct epitopes with a novel IL-1 inducible sialoglycoprotein which is implicated in the adhesion of T cells with activated endothelium (1). We used polymerase chain reaction (PCR, 2, 3...
متن کاملEmerging Roles of Vascular Cell Adhesion Molecule-1 (VCAM-1) in Immunological Disorders and Cancer.
Tumor necrosis factor alpha (TNFα) is a pro-inflammatory cytokine that triggers the expression of inflammatory molecules, including other cytokines and cell adhesion molecules. TNFα induces the expression of intercellular cell adhesion molecule-1 and vascular cell adhesion molecule-1 (VCAM-1). VCAM-1 was originally identified as a cell adhesion molecule that helps regulate inflammation-associat...
متن کاملCytokine stimulated vascular cell adhesion molecule-1 (VCAM-1) ectodomain release is regulated by TIMP-3.
OBJECTIVES Vascular cell adhesion molecule-1 (VCAM-1) is a cell surface adhesion molecule involved in the recruitment of leukocytes to endothelial cells on arterial walls during the pathogenesis of atherosclerosis. The soluble ectodomain of VCAM-1 (sVCAM-1) is proteolytically released from the cell surface into the circulation, a process which is up-regulated in patients with cardiovascular or ...
متن کاملserum level of vascular cell adhesion molecule-1 (svcam-1) in sera
endothelial dysfunction is thought to be a central pathogenic feature in preeclampsia on the basis of elevated adhesion molecules. soluble forms of these molecules can be detected in plasma, and their concentrations are thought to reflect the degree of activation of a particular cell type. the aim of the present study was to compare the levels of soluble vascular cell adhesion molecule-1 (svcam...
متن کاملExpression of intercellular adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1) on proliferating vascular endothelial cells in diabetic epiretinal membranes.
The present study demonstrated the expression of intercellular adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1), the proliferating status of the neovascular endothelial cells, and the activation of vascular endothelial cells bearing the two cell adhesion molecules in diabetic epiretinal membranes by using double immunofluorescence and APAAP techniques. The results sho...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 1990
ISSN: 0305-1048,1362-4962
DOI: 10.1093/nar/18.19.5901